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KMID : 0385019910070010009
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Korean Journal of Laboratory Animal Science
1991 Volume.7 No. 1 p.9 ~ p.14
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Use of the Rabbit Ear Model in Evaluating the Comedogenic Potential of Cosmetic Ingredients
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Abstract
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The external ear canal of the rabbit has been utilized to assess the comedogenic potential of ingredients used in the formulation of products applied to the skin. Some cosmetic raw materials have been shown to produce varying degrees of hyperkeratosis in the pihsebaseous unit of this animal model. The present study were performed to gain information relating to the comedogenic potential of cosmetic components and reevaluates the activity of two substances previously reported.
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